Defending champion Andrey Rublev was knocked out of the Monte Carlo Masters in a 6-4 6-4 second-round loss to Australian Alexei Popyrin on Wednesday as world number two Jannik Sinner eased through his first test.
Popyrin broke in the third game of the first set, but Rublev broke to take a 3-1 lead in the second, only for the Australian hit back immediately.
A further break made it 5-4 to Popyrin and he held serve to reach the third round for the first time. Russian fifth seed Rublev had received a bye into the second round.
Popyrin will face fellow Australian Alex de Minaur next, after the 11th seed beat Dutchman Tallon Griekspoor 2-6 6-2 6-3.
Italian Sinner, who won his first major title at the Australian Open in January, eased into the third round with a 6-1 6-2 win over American Sebastian Korda.
Korda won their last meeting, in Adelaide last year, but was no match for the in-form Sinner, who also won this year's Miami Open and Rotterdam Opens.
Sinner, who broke Korda in the opening game of the match and was never threatened, will next meet German Jan-Lennard Struff who he beat at Indian Wells in March.
Twice champion Stefanos Tsitsipas, the 12th seed, also reached the third round after crushing Tomas Etcheverry of Argentina 6-1 6-0 and will next face German fifth seed Alexander Zverev.
French 14th seed Ugo Humbert defeated China's Zhizhen Zhang 6-1 6-4, and will face Lorenzo Sonego in the third round after the Italian, brought in as a lucky loser to replace the injured Carlos Alcaraz, beat Canada's Felix Auger-Aliassime 6-4 7-5.

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