Bahrain will suspend dine-in services at restaurants and cafes and move public and private schools to remote learning for three weeks to contain the spread of the coronavirus, the health ministry said.
It said it had detected a new variant of coronavirus in a number of cases, without specifying which kind.
The new lockdown measures will come into effect on Sunday.
There has been an uptick in coronavirus cases in the Gulf kingdom since December. The country registered 459 new cases on Wednesday, adding to a total of nearly 100,000 since the start of the pandemic, with 370 deaths.
The small island state has the third highest rate of vaccinations per capita in the world so far, according to the Our World in Data website, which is run by an Oxford University research programme.
Bahrain offers its citizens either the Pfizer/BioNTech vaccine or one manufactured by Chinese state-backed pharmaceutical giant Sinopharm free of charge.
The kingdom also approved the AstraZeneca COVID-19 vaccine on Monday for emergency use.
The US State Department said on Friday it has approved a sale worth $151.8 million to Israel for munitions and munitions support, without submitting it for congressional review.
Flash floods across Nairobi overnight has left at least 23 people dead, authorities said, adding that dozens of cars were swept away and flights at East Africa's biggest airport disrupted.
Russia launched a barrage of drones and missiles at Ukraine overnight on Saturday, damaging infrastructure and killing at least 10 people in the northeast city of Kharkiv, Ukrainian officials said.
The Ministry of Defence said UAE air defences intercepted 15 of the 16 ballistic missiles detected in the region on Saturday, with one falling into the sea.
UAE President His Highness Sheikh Mohamed bin Zayed Al Nahyan has discussed the implications of the escalating military actions in the region for international security and stability during calls with leaders of Singapore and Nepal.
Dubai carrier flydubai said operations in and out of Dubai has resumed on Saturday after a brief suspension with passengers “requested not to travel to the airport unless they have a booking confirmation”.