According to manager Ole Gunnar Solskjaer, the France midfielder needs an operation on his ankle.
The 26-year-old only made his comeback last month, as his ankle problem kept him out since late September last year.
Scott McTominay is currently also out injured.
Pogba has played only eight times this season after having surgery to correct another ankle injury.


UAE beats Canada in T20 World Cup thriller
Zimbabwe stun Australia to stay unbeaten in T20 World Cup
Arsenal miss chance to go six points clear with draw at Brentford
India thump Namibia ahead of Pakistan clash
Italy crush Nepal in maiden T20 World Cup victory
